MUTIPLE LATENCY TEST
(USUALLLY AFTER PSG TO EXCLUDE NACROLEPSY)

Mean Sleep Latency	Episodes of sleep onset REM	Result
<=8 MINS	>=2	MULTIPLE SLEEP LATENCY TEST SHOWS COMPATIBLE WITH NARCOLEPSY.
	1	MULTIPLE SLEEP LATENCY TEST SHOWS PATHOLOGIC HYPERSOMNOLENCE WITH 1 SLEEP ONSET REM.
>8 MINS		MULTIPLE SLEEP LATENCY TEST SHOWS NOT COMPATIBLE WITH NARCOLEPSY.

 

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IF < 8MINS AND 2 EPISODES OF SLEEP ONSET REM:
MULTIPLE SLEEP LATENCY TEST SHOWS COMPATIBLE WITH NARCOLEPSY.

IF < 8 MINS AND 1 EPISODE OF SLEEP ONSET REM:
MULTIPLE SLEEP LATENCY TEST SHOWS PATHOLOGIC HYPERSOMNOLENCE WITH 1 SLEEP ONSET REM.

NEGATIVE:
MULTIPLE SLEEP LATENCY TEST SHOWS NOT COMPATIBLE WITH NARCOLEPSY.

MSLT多次入睡潛伏時間測試陽性(平均sleep latency<=8 minutes，至少兩次有發生SOREMP(REM latency<=15minutes)

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MSLT是診斷narcolepsy的重要工具又分type 1 及 type 2

	Symptom	Cataplexy	MSLT	hypocretin	排除條件
Type1	白天嗜睡>=3個月	+	+	+/-
		+/-	+/-	<=110pg/mL or <1/3 mean of normal
Type2		-	+	正常	insufficient sleep, obstructive sleep apnea, delayed sleep phase disorder, or the effect of medication or substances or their withdrawal

Type 1(典型):cataplexy or hypocretin-1 deficiency

Type 2(其他):排除type 1且排除其他原因